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The decision of when to start B12 injections is individual and depends on factors like the severity of the deficiency, the underlying cause, and the patients health status

B12 is contraindicated in Lebers Disease (a hereditary optic nerve atrophic condition), clients with chronic liver and/or kidney dysfunction, or abnormal red blood cells (megaloblastic anemia)

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PMCID: PMC12944561

This is thought to affect angiogenic activity, fibroblast behavior, and collagen organization in tissue repair models

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