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GLP-1 receptor agonists function by mimicking a hormone that targets areas of the brain involved in appetite regulation
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First Approval Drugs
The supramammillary nucleus, located in the hypothalamus, is a new candidate that appears to be responsible for GLP-1 mediated anxiety effects because selective activation of GLP-1Rs in this nucleus by exendin-4 resulted in intensified anxiety-like behavior both in male and female rats
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