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Common side effects include, but may not be limited to: pain or redness at the injection site mild diarrhea pruritus (itching) increased swelling joint pain dizziness headache nervousness or anxiety Serious side effects may include: allergic reactions peripheral vascular thrombosis hypokalemia (low potassium levels) pulmonary edema (fluid build-up around or in the lungs) thrombocytosis congestive heart failure There have been reports of anaphylactic shock and death after the parenteral administration of vitamin B12

B Vitamins Can Reduce Body Weight Gain by Increasing Metabolism-related Enzyme Activities in Rats Fed on a High-Fat Diet

[9] Observations researchers have made following testing imply that TB-500 might increase the expression of interleukin-1 (IL-1) and interleukin-6 (IL-6) mRNA in the corneal tissues of injured murine models

(6) Hyun Keol Pyo, Hyeon Gyeong Yoo, Chong Hyun Won, Seung Ho Lee, et al (2007) The effect of tripeptide-copper complex on human hair growth in vitro Archives of Pharmacal Research, 2007 Jul, Volume 30 (Issue 7), Pages 834-9

For antigen delivery, a modified vaccinia Ankara (MVA) virus and adjuvanted protein subunit approach in a heterologous prime-boost regimen were selected, as this has been proposed to elicit stronger, broader and/or longer-lasting immunity than homologous vaccinations 29

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