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250 A multicenter, randomized, double-blind, placebo-controlled phase II study validated that RT100, an AdV5-encoded AC6 gene therapy, safely increased left ventricular function beyond standard HF treatments

Activation of 5'-AMP-activated protein kinase (AMPK) signaling by GLP-1RA weakened AD-related phenotypes in transgenic mice, reduced -secretase-mediated (BACE1) cleavage of the amyloid precursor protein (APP) and the formation of -amyloid peptides

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The work, conducted in mice, shows that antioxidants can change cells in ways that fuel the spread of malignant melanomathe most serious skin cancerto different parts of the body

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