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Moreover, excess copper can directly oxidize glutathione, leading to its depletion

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Finally, a four-year, multicenter, clinical trial in 421 diabetic patients with distal symmetric sensorimotor polyneuropathy found no difference between oral administration of 600 mg/day of lipoic and placebo on the primary endpoint, a composite score that assessed neuropathic impairment of the lower limbs and nerve conduction (78)

Eriksson JG, Forsen TJ, Mortensen SA, et al

Children 9-13 Years 1.8 mcg

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