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Clinical data suggest this produces greater average weight loss compared to semaglutide alone

This dual mechanism is the pharmacological reason tirzepatide produces greater average weight loss than GLP-1 single-agonists in clinical trial data

Metabolic reactions: It plays a fundamental role in carrying out numerous metabolic and biochemical reactions

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This broad receptor distribution underlies the pleiotropic research profile of GLP-1 from appetite and reward behaviour regulation in the central nervous system, to cardioprotective effects in cardiac tissue, to anti-inflammatory and immunomodulatory activity in immune cell models