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ShiZZHabibGMRheadWJGahlWAHeXSazerSet alMutations in the glutathione synthetase gene cause 5-oxoprolinuria

Injectable administration is hypothesized to provide systemic distribution, but human pharmacokinetic data for this route does not exist

This allows for more histidine residues to be exposed for binding than normal, leading to the ability to strip away copper from other copper binding proteins such as albumin (Jiang et al., 2013)

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