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This is due to an excessive amount of calcified black tartar accumulated under the gum tissue, which may result in the black appearance near the gums, but the gums themselves do not have discoloration
10.1016/j.toxlet.2015.05.001 109 WangY.ZhaoY.WangZ.SunR.ZouB.LiR.et al (2021)
Although choline, betaine and carnitine can predict the risk of future MACE, this association appears to be primarily driven by the gut microbiota-derived metabolite TMAO [3, 4]
Yes, it is made and quality tested in the USA with globally sourced ingredients