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doi: 10.1056/NEJM199205143262003 34 GjesingAPEkstrmCTEibergHUrhammerSAHolstJJPedersenOet al

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The terminal product of the complement cascade, the membrane attack complex (MAC, also known as C5b-9), directly disrupts the integrity of the cell membrane by forming transmembrane pores on target cells such as vascular endothelial cells (123)

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