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doi: 10.1002/JLB.MR0618-213R 245 SchieberM.ChandelN

Single-cell maps reveal novel mechanisms of ferroptosis and biomarkers in diabetic nephropathy

The measured targets included 85 with a previous type 1 diabetes association, in addition to 13 selected for reference or otherwise

PMID: 24818783 9

The coordinates of the -SO 2 H group (wherein the sulfur center adopts the pyramidal geometry and features the lone pair of electrons) were oriented to best fit the map while maximizing polar interactions with the surrounding YPEL5 side chains

This process may explain why some patients respond to methylcobalamin but NOT cyanocobalamin