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(2018) 48:812830.e14
Comorbidities (hypertension, stroke, acute myocardial infarction, chronic kidney disease, dyslipidemia, and liver disease) were defined using ICD-10 codes, prescription data, and national health screening examination data
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While short-term LC supplementation has demonstrated positive effects, including increased endurance, improved hepatic fat metabolism, and myocardial stability, evidence indicates that the prolonged supplementation may pose risks, particularly for individuals with pre-existing cardiovascular or renal conditions
