Yes, DSIP has been shown to cross the blood-brain barrier and has been detected in multiple brain regions including the hypothalamus and limbic structures
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Bayley EM, Zhou N, Mitchell KG, Antonoff MB, Mehran RJ, Rice DC, Sepesi B, Swisher SG , Vaporciyan AA, Walsh GL, Cinciripini PM, Karam-Hage M, Roth JA, Hofstetter WL
The FDA label recommends supportive care rather than a specific antidote, and observational data on GLP-1 class medications show only about 6 percent of accidental exposures lead to serious outcomes
The study was funded by WW International
Rigault C, Dias JV, Demarquoy J, Le Borgne F