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The 1.4% gallbladder complication rate from trials occurred with standard titration
Before using it, let your doctor know if you have any pancreas or stomach problems or severe dehydration (loss of body water), or diabetic ketoacidosis (a complication of diabetes characterized by too much acid and ketones in your blood)
Potential metabolic benefits: As a vitamin B3 derivative, niacinamide itself has some metabolic effects that may complement tirzepatide's action
However, changes in urinary frequency can occur indirectly as blood glucose levels improve or if diabetes remains poorly controlled
But research currently lags behind the trend, with the evidence around tirzepatides effectiveness based on therapeutic doses of at least 2mg
Your doctor will check how youre doing during this time
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