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Parenteral and intranasal cyanocobalamin, vitamin B12 are classified as pregnancy category C
It is prescribed off-label based on clinician judgment and emerging research
Against Matrixyl 3000: Badenhorst 2016 reported that GHK-Cu produced 31.6% greater wrinkle volume reduction in head-to-head testing
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Patients with vitamin B12 deficiency and concurrent renal or hepatic disease may require increased doses or more frequent administration of cyanocobalamin
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