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Furthermore, after transfer into LLC1-OVA tumorbearing mice, the greatest numbers of IFN-producing intratumoral CD8 + T cells were observed in mice that received A2ARi-treated GCLC-overexpressing CD8 + T cells (Figure 2P) accompanied by a decrease in tumor burden compared with other groups of mice (Figure 2Q)

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For context, about 60% of CagriSema participants hit the 20% weight-loss mark, and nearly 1 in 4 lost 30% or more