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Statements Author contributions SC-J and MM wrote the manuscript
Both activate AMPK, but through distinct mechanisms: metformin inhibits complex I of the mitochondrial electron transport chain, raising the cellular AMP:ATP ratio and thereby activating AMPK indirectly
Reconstituted volume is effectively the water you added
Thus, only 1300 cm 3 of plasma was removed versus 2600 cm 3
As we explained previously, usually the positive impact of cobalamine shots can be felt in several days
These pathways complement each other, creating a stronger overall effect
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