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PMID: 39695227 Cell 2025 Jan 23;188(2):412-429.e27

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It may be administered safely for longer periods, as well

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Yans group constructed an amphiphilic conjugate (ZEGFR:1907-MS28) by linking a hydrophilic EGFR-targeting moiety to a hydrophobic PROTAC (MS28) via a disulphide bond, which spontaneously assembles into nanodrugs ( ADCNs ) (Fig