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Another possibility of the direct effects of GLP-1 and ghrelin in the brain has been proposed since both peptides cross the brain blood barrier 25,35
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GLP-1 receptor agonists (GLP-1RAs) are currently used for treating type-2 diabetes and obesity because of their effects on appetite, food intake, and body weight loss
Your body naturally produces GLP-1 in your gut with receptor sites all over your body- brain, bone, blood vessels, heart, and many other places throughout your body
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