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At the cellular level, GLP-1 receptor activation appears to reduce the production of pro-inflammatory cytokines such as tumor necrosis factor-alpha (TNF-), interleukin-6 (IL-6), and interleukin-1 beta (IL-1)

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Summary Retatrutide (LY3437943) is a groundbreaking investigational peptide therapy that activates three key metabolic hormone receptorsGLP-1, GIP, and glucagondelivering unprecedented weight loss outcomes

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10.1016/j.ijpharm.2023.123334 3 AldawoodF

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