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To achieve this, these enzymes can bind non-substrate ligands (ligandin function) and/or catalyze the conjugation of glutathione onto the targeted molecules, the latter activity being exhibited by GSTs having a serine or a tyrosine as catalytic residues

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Discussion Pathological myocardial hypertrophy is characterized by the death of myocardial cells and concomitant fibrosis that ultimately leads to reductions in systolic and diastolic function, contributing to the onset and progression of heart failure