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Research Applications of Tirzepatide Dual GIP and GLP-1 receptor binding studies in HEK293 cells co-expressing both receptors, where tirzepatide is the standard reference compound for examining biased agonism, receptor cross-talk, and the imbalanced activity profile that distinguishes it from balanced co-agonists
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Tirzepatide (Mounjaro, Zepbound), a dual GIP/GLP-1 receptor agonist, is substantially eliminated from the body within 23 weeks of discontinuation
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