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Because these come from separate trials with different participants, the figures cant be read as a direct comparison
Approval (2017) Mechanisms of GLP-1 Receptor Agonist-Induced Weight Loss: A Review of Central and Peripheral Pathways in Appetite and Energy Regulation (May 17, 2025) Semaglutide (February 11, 2024) Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Adults With Overweight or Obesity: The STEP 4 Randomized Clinical Trial (March 23, 2021) Weight Regain And Cardiometabolic Effects After Withdrawal Of Semaglutide: The Step 1 Trial Extension (May 19, 2022)
What If UnitedHealthcare Denies My GLP-1 Prescription
This does not mean you must take semaglutide forever, but it does mean that discontinuation should be planned carefully
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