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In humans with obesity, levels of GLP-1, and to a lesser extent GIP, increased after diet-induced weight loss in some [58, 59], but not all [60], studies

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While standard berberine studies typically use 1,000-1,500mg daily, the improved absorption of dihydroberberine means a lower dose may achieve similar metabolic effects

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GLP-1 RA (glucagon-like peptide-1 receptor agonists) are associated with decreased cardiovascular disease, mainly driven by reduced stroke risk, and have gained interest as therapeutic agents for stroke recovery in experimental stroke models

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