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Although combined therapy is still not common practice because of the relatively recent regulatory approval, these studies highlight the potential of dual GLP-1 RA + SGLT2i therapy to synergistically reduce cardiovascular disease and decelerate renal decompensation [75]

It suggests asking whether the aches began within days of starting or weeks after an increase, whether they localize to weight-bearing joints or spread across muscle groups, and whether they improve or worsen with hydration, electrolyte replacement, and movement

Looking Ahead: The Future of Oral GLP-1 Receptor Agonists The future of oral GLP-1 receptor agonists in diabetes care is promising, with ongoing advancements poised to enhance their impact

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Cardiovascular safety of the dipetidyl peptidase-4 inhibitor alogliptin in type 2 diabetes mellitus