In contrast, we found a larger amount of evidence over 26 studies assessing depressive symptoms in populations with comorbid physical health conditions undergoing GLP-1RA treatment (Table 5)
For example, initiating therapy soon after diagnosis could improve glycemic control before significant beta-cell decline occurs
Gwern Supplementary Appendix (Peer-Reviewed Study Supplement NEJM) Supplement to: Jastreboff AM, Kaplan LM, Fras JP, et al
Redox Biology 26: 101294
All trials enrolled patients with type 2 diabetes, not obesity alone
Myhre O, Andersen JM, Aarnes H, Fonnum F (2003) Evaluation of the probes 2,7-dichlorofluorescin diacetate, luminol, and lucigenin as indicators of reactive species formation