Live ex vivo tissue imaging Adult mice (P100-P120) of both sexes were used in the study
287(c) | Oblon Life Science, accessed December 19, 2025, Research Use Exemptions to Patent Infringement for Drug Discovery and Development in the United States PMC NIH, accessed December 19, 2025, The Safe Harbor for FDA Submissions Expands: Did the Federal Circuit Reverse Course
Pinto, an obesity and family medicine doctor at Johns Hopkins Medicine in Baltimore, who wasnt involved in the research
While our efforts to define the endogenous ligand for NHR-49 were unsuccessful, mutating the ligand-binding pocket might allow us to determine the role of ligand binding in the transcriptional activity of NHR-49
Semaglutide is a prescription medication approved by the FDA for the treatment of obesity
Peters et al., 1977