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1 Heart-rate changes can persist longer but tend to plateau or decline as treatment continues

Ozempic 0.25 mg or 0.5 mg dose (2 mg/3 mL subcutaneous pen injector) NDC: 0169-4181-13 Days supply: Sample/initial (42 days) 1-month supply (28 days) Intent of prescription: Sample or initial prescription for new starts 1-month prescription for maintenance on 0.5 mg For patients with T2D and CKD, increase to the recommended maintenance dose of 1 mg after at least 4 weeks on 0.5 mg Strength: 2 mg per 3 mL (0.68 mg/mL) Dosage form: Solution SIG: Sample or initial Rx: Inject 0.25 mg SUBQ once weekly for 4 weeks, then 0.5 mg SUBQ once weekly for 2 weeks Maintenance Rx: Inject 0.5 mg SUBQ once weekly for 4 weeks Dispense quantity: 3 mL Dispense quantity unit of measure: mL ONLY Needles: 6 included Number of boxes: 1 box Ozempic 0.25 mg or 0.5 mg dose (2 mg/3 mL subcutaneous pen injector) NDC: 0169-4181-13 Days supply: 3-month supply (84 days) Intent of prescription: 3-month prescription for maintenance on 0.5 mg For patients with T2D and CKD, increase to the recommended maintenance dose of 1 mg after at least 4 weeks on 0.5 mg Strength: 2 mg per 3 mL (0.68 mg/mL) Dosage form: Solution SIG: Maintenance Rx: Inject 0.5 mg SUBQ once weekly for 12 weeks Dispense quantity: 9 mL Dispense quantity unit of measure: mL ONLY Needles: 18 included Number of boxes: 3 boxes Ozempic 1 mg dose (4 mg/3 mL subcutaneous pen injector) NDC: 0169-4130-13 Days supply: 1-month supply (28 days) Intent of prescription: 1-month prescription for maintenance on 1 mg Strength: 4 mg per 3 mL (1.34 mg/mL) Dosage form: Solution SIG: Maintenance Rx: Inject 1 mg SUBQ once weekly for 4 weeks Dispense quantity: 3 mL Dispense quantity unit of measure: mL ONLY Needles: 4 included Number of boxes: 1 box Ozempic 1 mg dose (4 mg/3 mL subcutaneous pen injector) NDC: 0169-4130-13 Days supply: 3-month supply (84 days) Intent of prescription: 3-month prescription for maintenance on 1 mg For patients with T2D and CKD, increase to the recommended maintenance dose of 1 mg Strength: 4 mg per 3 mL (1.34 mg/mL) Dosage form: Solution SIG: Maintenance Rx: Inject 1 mg SUBQ once weekly for 12 weeks Dispense quantity: 9 mL Dispense quantity unit of measure: mL ONLY Needles: 12 included Number of boxes: 3 boxes Ozempic 2 mg dose (8 mg/3 mL subcutaneous pen injector) NDC: 0169-4772-12 Days supply: 1-month supply (28 days) Intent of prescription: 1-month prescription for maintenance on 2 mg Strength: 8 mg per 3 mL (2.68 mg/mL) Dosage form: Solution SIG: Maintenance Rx: Inject 2 mg SUBQ once weekly for 4 weeks Dispense quantity: 3 mL Dispense quantity unit of measure: mL ONLY Needles: 4 included Number of boxes: 1 box Ozempic 2 mg dose (8 mg/3 mL subcutaneous pen injector) NDC: 0169-4772-12 Days supply: 3-month supply (84 days) Intent of prescription: 3-month prescription for maintenance on 2 mg Strength: 8 mg per 3 mL (2.68 mg/mL) Dosage form: Solution SIG: Maintenance Rx: Inject 2 mg SUBQ once weekly for 12 weeks Dispense quantity: 9 mL Dispense quantity unit of measure: mL ONLY Needles: 12 included Number of boxes: 3 boxes Saving Ozempic as a favorite in the EHR as a favorite in the EHR If your EHR allows you to save your frequently used prescriptions to a "favorites" list, be sure to add Ozempic pen for quicker access

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Even in that population, retatrutide demonstrated nearly 21 percent average weight loss at the highest dose, which is remarkable. Retatrutide Also Delivered Significant Results for People With Severe Obesity and Heart Disease The other trial, TRIUMPH-3, included nearly 2,000 adults with severe obesity (defined as a BMI of 40 or higher) and cardiovascular disease

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